The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 02, 2019
Filed:
Dec. 29, 2015
Applicant:
University of Iowa Research Foundation, Iowa City, IA (US);
Inventors:
Satheesh Elangovan, Iowa City, IA (US);
Sheetal Reginald R D'mello, Silver Spring, MD (US);
Anh-Vu T Do, Iowa City, IA (US);
Liu Hong, Coralville, IA (US);
Behnoush Khorsand-Sourkohi, Iowa City, IA (US);
Aliasger K Salem, Coralville, IA (US);
Michael Kormann, Tübingen, DE;
Assignee:
University of Iowa Research Foundation, Iowa City, IA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); A61L 27/54 (2006.01); A61L 27/58 (2006.01); A61K 31/7115 (2006.01); A61K 31/712 (2006.01); A61K 38/18 (2006.01); A61K 9/50 (2006.01); A61L 27/26 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
A61K 48/0041 (2013.01); A61K 31/712 (2013.01); A61K 31/7115 (2013.01); A61K 48/00 (2013.01); A61K 48/005 (2013.01); A61L 27/54 (2013.01); A61L 27/58 (2013.01); A61K 38/00 (2013.01); A61L 2300/258 (2013.01); A61L 2300/414 (2013.01); A61L 2300/62 (2013.01); A61L 2430/02 (2013.01);
Abstract
The present disclosure provides compositions and methods useful for tissue engineering including a composition having chemically modified RNA (cmRNA) encapsulated in or complexed with a non-viral delivery vehicle and a biocompatible, bioresorbable scaffold and methods of using the composition to regenerate, for example, bone tissue.