The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 02, 2019

Filed:

Aug. 22, 2018
Applicant:

D. R. Nano Co., Ltd., Seoul, KR;

Inventors:

Sehoon Kim, Seoul, KR;

Ick Chan Kwon, Seoul, KR;

Sangyoup Lee, Seoul, KR;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61B 8/00 (2006.01); A61K 41/00 (2006.01); A61K 49/00 (2006.01); A61K 9/51 (2006.01); A61K 9/00 (2006.01); A61P 35/00 (2006.01); A61K 47/32 (2006.01); A61K 47/54 (2017.01);
U.S. Cl.
CPC ...
A61K 41/0057 (2013.01); A61K 9/0019 (2013.01); A61K 9/5123 (2013.01); A61K 9/5138 (2013.01); A61K 47/32 (2013.01); A61K 47/542 (2017.08); A61K 49/003 (2013.01); A61K 49/006 (2013.01); A61K 49/0093 (2013.01); A61P 35/00 (2018.01); A61K 49/0082 (2013.01);
Abstract

The present invention discloses a method for treating cancer disease by photodynamic therapy. The photodynamic therapy in the present invention uses a methylene blue nanoparticle as a therapeutic agent. The methylene blue nanoparticle of the present invention for use as a topical cancer targeting phototherapeutic agent is composed of only a material of which the composition is clinically used or derived from human bodies, and thus a nanopreparation in which a barrier to clinical entry is low and the possibility of commercialization is very high, exhibits near-infrared fluorescence along with cancer targeting property, capacity of generating a singlet oxygen and the like. Therefore, the methylene blue nanoparticle in the present invention is able to cure cancer cells by cell apoptosis in irradiation conditions.


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