The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 02, 2019

Filed:

Dec. 22, 2014
Applicant:

Board of Regents, the University of Texas System, Austin, TX (US);

Inventors:

Pomila Singh, Houston, TX (US);

Gurpreet Singh, Houston, TX (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 38/22 (2006.01); C07K 14/595 (2006.01); C07K 16/26 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 39/0011 (2013.01); A61K 38/2207 (2013.01); A61K 39/0005 (2013.01); A61K 45/06 (2013.01); C07K 14/595 (2013.01); C07K 16/26 (2013.01); C07K 2317/77 (2013.01);
Abstract

The present invention is drawn to immunotherapeutic methods to treat tumors/cancers that produce progastrin ectopically or are dependent on progastrin for their growth. Disclosed herein are immunogenic compositions comprising agents that target progastrin, agents that target the progastrin receptor, annexin II, or both. Such a composition may be administered in combination with chemotherapy or to an individual who had been previously subjected to chemotherapy or radiation therapy. The cancers that may be treated using such a composition may include but are not limited to colon cancer, breast cancer, lung cancer or pancreatic cancer.


Find Patent Forward Citations

Loading…