The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 02, 2019

Filed:

Jan. 26, 2018
Applicant:

U.s. Army Edgewood Chemical Biological Center, Washington, DC (US);

Inventors:

Steven P Harvey, Lutherville, MD (US);

Melissa M Dixon, Abingdon, MD (US);

Mark A Guelta, White Marsh, MD (US);

Leslie R McMahon, Aberdeen, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/16 (2006.01); A61K 38/16 (2006.01); A62D 7/00 (2006.01); A61K 38/46 (2006.01); A62D 3/02 (2007.01); A62D 101/26 (2007.01); A62D 101/02 (2007.01);
U.S. Cl.
CPC ...
A61K 38/465 (2013.01); A62D 3/02 (2013.01); A62D 2101/02 (2013.01); A62D 2101/26 (2013.01);
Abstract

The invention is directed toward mutant, non-wild-type organophosphorus acid anhydrolase enzymes having three site mutations, methods of production, and methods of use to effectively degrade toxic organophosphorus compounds, most preferably GP (2,2'-dimethylcyclopentyl methylphosphonofluoridate).


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