The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 02, 2019
Filed:
Jun. 22, 2017
Alkermes, Inc., Waltham, MA (US);
Demetri T. Moustakas, Belmont, MA (US);
Mark N. Namchuk, Arlington, MA (US);
Heather C. Losey, Lexington, MA (US);
Juan C. Alvarez, Lincoln, MA (US);
Alkermes, Inc., Waltham, MA (US);
Abstract
The invention provides compositions and methods for modulating the immunostimulatory properties and/or anti-inflammatory properties of IL-10. The present invention provides scIL-10 polypeptides of Formula 1. The polypeptides of the invention are optionally linked to a fusion partner. The polypeptides of Formula 1 are referred to herein as 'scIL-10' polypeptides and comprise an amino acid sequence arrangement from N-terminus to C-terminus in accordance with Formula 1:(first monomer subunit)-LINKER-(second monomer subunit)   Formula 1