The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 02, 2019
Filed:
Mar. 09, 2014
Jcr Pharmaceuticals Co., Ltd., Ashiya-shi, Hyogo, JP;
Kyoto Prefectural Public University Corporation, Kamigyo-ku, Kyoto-shi, Kyoto, JP;
Kiwamu Imagawa, Hyogo, JP;
Kenichi Maeda, Hyogo, JP;
Yuki Hosoda, Hyogo, JP;
Shuichi Yokoyama, Hyogo, JP;
Naoki Okumura, Kyoto, JP;
Noriko Koizumi, Kyoto, JP;
Shigeru Kinoshita, Kyoto, JP;
JCR Pharmaceuticals Co., Ltd., Ashiya-shi, Hyogo, JP;
Kyoto Prefectural Public University Corporation, Kyoto-shi, Kyoto, JP;
Abstract
[Problem] To provide a method for producing human corneal epithelial sheet, wherein the human corneal epithelial-derived cells obtained by culturing human corneal epithelial cells are cultured on an amnion substrate. [Solution] A method for culturing human corneal epithelial cells using mesenchymal stem cells as the feeder cells; and a method for culturing human corneal epithelial cells using a medium containing a ROCK inhibitor, a phosphodiesterase inhibitor, a MAP kinase inhibitor and a TGF-β receptor inhibitor in various combinations.