The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 25, 2019

Filed:

Apr. 12, 2017
Applicant:

The Johns Hopkins University, Baltimore, MD (US);

Inventor:

Qin Qin, Ellicott City, MD (US);

Assignee:

The Johns Hopkins University, Baltimore, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01V 3/00 (2006.01); G01R 33/50 (2006.01); G01R 33/56 (2006.01); G01R 33/563 (2006.01);
U.S. Cl.
CPC ...
G01R 33/50 (2013.01); G01R 33/5601 (2013.01); G01R 33/5607 (2013.01); G01R 33/56366 (2013.01);
Abstract

The present invention is directed to a system and method for measuring blood volume using non-contrast-enhanced magnetic resonance imaging. The method of the present invention includes a subtraction-based method using a pair of acquisitions immediately following velocity-sensitized pulse trains for the label module and its corresponding control module, respectively. The signal of static tissue is canceled out and the difference signal comes from the flowing blood compartment above a cutoff velocity. After normalizing to a proton density-weighted image acquired separately and scaled with the blood T1 and T2 relaxation factors, quantitative measurement of blood volume is then obtained.


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