The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 25, 2019

Filed:

May. 06, 2016
Applicant:

Hoffmann-la Roche Inc., Little Falls, NJ (US);

Inventors:

Andrea Challand, Penzberg, DE;

Christian Klein, Bonstetten, CH;

Manfred Kubbies, Penzberg, DE;

Assignee:

Hoffmann-La Roche Inc., Little Falls, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/50 (2006.01); G01N 33/49 (2006.01);
U.S. Cl.
CPC ...
G01N 33/5014 (2013.01); G01N 33/4915 (2013.01); G01N 33/5017 (2013.01); G01N 33/5044 (2013.01); G01N 33/5047 (2013.01);
Abstract

Herein is reported a cell analytical technology based on a three-dimensional spheroid/aggregate co-culture assay, wherein the spheroid or aggregate is formed of tumor and natural killer cells. This method is useful for the in vitro functional analysis of antibodies in single and high-throughput format.


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