The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 25, 2019

Filed:

Jul. 31, 2015
Applicant:

Wisconsin Alumni Research Foundation, Madison, WI (US);

Inventors:

Robert H. Blick, Hamburg, DE;

Paul H. Gwozdz, Hamburg, DE;

Abhishek Bhat, Madison, WI (US);

Wolfgang Hansen, Hamburg, DE;

Christian Heyn, Lueneburg, DE;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 27/327 (2006.01); C12Q 1/6869 (2018.01); G01N 21/64 (2006.01); G01N 33/487 (2006.01); G01N 30/88 (2006.01); B82Y 15/00 (2011.01);
U.S. Cl.
CPC ...
G01N 27/3278 (2013.01); C12Q 1/6869 (2013.01); G01N 21/6408 (2013.01); G01N 33/48721 (2013.01); B82Y 15/00 (2013.01); G01N 21/6489 (2013.01); G01N 2030/8827 (2013.01);
Abstract

A nanoscale-sized pore positioned between two reservoirs may sequence biomolecules by detecting changes in the emitted light due to a change in charge of portions of the biomolecules as they pass through the pore such as affect an emission frequency of a quantum structure proximate to the pore opening. The nanopores may be fabricated using local droplet etching whose randomness is accommodated by lowering the droplet density to permit isolation of nanopores in tiles that may be adhered to an underlying supporting substrate having an aligned opening. The nanopore-tiles may be integrated with commonly applied glass chips and may be employed in microfluidic circuitry.


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