The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 25, 2019

Filed:

Mar. 05, 2018
Applicant:

Intelligent Bio-systems, Inc., Waltham, MA (US);

Inventors:

Steven Gordon, Weston, MA (US);

Jerzy Olejnik, Brookline, MA (US);

Assignee:

Intelligent Bio-Systems, Inc., Waltham, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2018.01); C12Q 1/6869 (2018.01); C07H 19/00 (2006.01); G01N 21/05 (2006.01); G01N 21/64 (2006.01); C12Q 1/6874 (2018.01); G01N 21/03 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6869 (2013.01); C07H 19/00 (2013.01); C12Q 1/6874 (2013.01); G01N 21/05 (2013.01); G01N 21/645 (2013.01); G01N 21/6428 (2013.01); C12Q 2535/101 (2013.01); G01N 2021/0346 (2013.01); G01N 2021/058 (2013.01); G01N 2021/6417 (2013.01); G01N 2021/6419 (2013.01); G01N 2021/6421 (2013.01); G01N 2021/6439 (2013.01); G01N 2021/6441 (2013.01); G01N 2021/6471 (2013.01); G01N 2201/062 (2013.01); G01N 2201/0627 (2013.01); G01N 2201/12 (2013.01);
Abstract

The invention provides methods and compositions, including, without limitation, algorithms, computer readable media, computer programs, apparatus, and systems for determining the identity of nucleic acids in nucleotide sequences using, for example, data obtained from sequencing by synthesis methods. The methods of the invention include correcting one or more phenomena that are encountered during nucleotide sequencing, such as using sequencing by synthesis methods. These phenomena include, without limitation, sequence lead, sequence lag, spectral crosstalk, and noise resulting from variations in illumination and/or filter responses.


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