The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 25, 2019
Filed:
Jul. 31, 2015
Applicants:
Academia Sinica, Taipei, TW;
National Taiwan University, Taipei, TW;
Inventors:
Assignees:
Academia Sinica, Taipei, TW;
National Taiwan University, Taipei, TW;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/11 (2006.01); C12N 15/115 (2010.01); A61K 31/7088 (2006.01); C12N 15/113 (2010.01); A61K 31/713 (2006.01); C12N 15/117 (2010.01); A61K 47/60 (2017.01);
U.S. Cl.
CPC ...
C12N 15/115 (2013.01); A61K 31/7088 (2013.01); A61K 31/713 (2013.01); A61K 47/60 (2017.08); C12N 15/117 (2013.01); C12N 15/1138 (2013.01); C12N 2310/16 (2013.01); C12N 2310/17 (2013.01); C12N 2310/351 (2013.01);
Abstract
Aptamers that bind to and antagonize programmed cell death protein 1 (PD-1). Also provided herein are pharmaceutical compositions comprising such anti-PD-1 aptamers and methods for using the same for promoting T cell proliferation, treating cancer or infectious diseases, such as human immunodeficiency virus (HIV) infection.