The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 25, 2019

Filed:

Jul. 12, 2016
Applicant:

Nanosniff Technologies Pvt. Ltd., Mumbai, IN;

Inventors:

Nitin Kale, Mumbai, IN;

Sumona Dhara, Thane, IN;

Dadasaheb Sangave, Solapur, IN;

Kapil Bardeja, Greater Noida, IN;

Assignee:

Other;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C08J 7/12 (2006.01); G01N 33/487 (2006.01); A61K 39/395 (2006.01); C07K 16/18 (2006.01); G01N 33/543 (2006.01); C08G 77/388 (2006.01); C08L 23/06 (2006.01); C08L 25/06 (2006.01); C08L 27/06 (2006.01); C08L 33/12 (2006.01);
U.S. Cl.
CPC ...
C08J 7/12 (2013.01); A61K 39/39533 (2013.01); C07K 16/18 (2013.01); G01N 33/48728 (2013.01); G01N 33/48785 (2013.01); G01N 33/54353 (2013.01); G01N 33/54373 (2013.01); G01N 33/54393 (2013.01); C08G 77/388 (2013.01); C08L 23/06 (2013.01); C08L 25/06 (2013.01); C08L 27/06 (2013.01); C08L 33/12 (2013.01);
Abstract

An asymmetric immobilization process that immobilizes a one or more receptor biomolecules on one or more solid surfaces is provided. The asymmetric immobilization process includes the following steps: (i) activating the one or more solid surfaces using an oxidizing agent; (ii) treating the one or more solid surfaces with aminosilane to obtain a one or more amine functionalized solid surfaces; (iii) treating the one or more receptor biomolecules with a 1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC) to obtain a one or more site-specific EDC activated receptor biomolecules; and (iv) immobilizing the one or more site-specific EDC activated receptor biomolecules on a first layer of the one or more amine functionalized solid surfaces, wherein the immobilizing comprises treating the one or more site-specific EDC activated receptor biomolecules with amine groups of the first layer of the one or more amine functionalized solid surfaces to form a covalent amide bond.


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