The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 25, 2019
Filed:
Jun. 12, 2017
Applicants:
Nippon Shinyaku Co., Ltd., Kyoto-shi, Kyoto, JP;
National Center of Neurology and Psychiatry, Kodaira-shi, Tokyo, JP;
Inventors:
Naoki Watanabe, Tsukuba, JP;
Youhei Satou, Tsukuba, JP;
Shin'ichi Takeda, Kodaira, JP;
Tetsuya Nagata, Kodaira, JP;
Assignees:
NIPPON SHINYAKU CO., LTD., Kyoto-shi, Kyoto, JP;
NATIONAL CENTER OF NEUROLOGY AND PSYCHIATRY, Kodaira-shi, Tokyo, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); A61K 31/70 (2006.01); C12N 15/11 (2006.01); C12N 15/113 (2010.01); C07H 21/00 (2006.01); C12N 5/00 (2006.01);
U.S. Cl.
CPC ...
C07H 21/04 (2013.01); C07H 21/00 (2013.01); C12N 15/111 (2013.01); C12N 15/113 (2013.01); C12N 2310/11 (2013.01); C12N 2310/315 (2013.01); C12N 2310/3145 (2013.01); C12N 2310/321 (2013.01); C12N 2310/3525 (2013.01); C12N 2320/33 (2013.01);
Abstract
The present invention provides an oligomer which efficiently enables to cause skipping of the 53rd exon in the human dystrophin gene. Also provided is a pharmaceutical composition which causes skipping of the 53rd exon in the human dystrophin gene with a high efficiency.