The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 25, 2019
Filed:
Oct. 11, 2013
Applicants:
The Brigham and Women's Hospital, Inc., Boston, MA (US);
President and Fellows of Harvard College, Cambridge, MA (US);
Inventors:
Dennis L. Kasper, Brookline, MA (US);
Dingding An, Brookline, MA (US);
Sungwhan Oh, Brookline, MA (US);
Richard S. Blumberg, Waltham, MA (US);
Torsten Olszak, Munich, DE;
Joana F. Neves, London, GB;
Assignees:
The Brigham and Women's Hospital, Inc., Boston, MA (US);
President and Fellows of Harvard College, Cambridge, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 15/04 (2006.01); A61K 31/7028 (2006.01); A61K 35/17 (2015.01); A61K 31/70 (2006.01); A61K 38/17 (2006.01); A61K 45/06 (2006.01); C12N 5/0783 (2010.01);
U.S. Cl.
CPC ...
C07H 15/04 (2013.01); A61K 31/70 (2013.01); A61K 31/7028 (2013.01); A61K 35/17 (2013.01); A61K 38/177 (2013.01); A61K 45/06 (2013.01); C12N 5/0646 (2013.01); C12N 2502/11 (2013.01);
Abstract
The invention provides, inter alia, immunoinhibitory glycosphingolipids and immunoinhibitory alpha-galactosylceramides and compositions and preparations thereof, and methods of use thereof including in the treatment of conditions characterized by increased iNKT cells and/or activity.