The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 25, 2019
Filed:
Mar. 06, 2018
Applicant:
Incyte Corporation, Wilmington, DE (US);
Inventors:
Shili Chen, Newark, DE (US);
William Frietze, Kennett Square, PA (US);
Zhongjiang Jia, Kennett Square, PA (US);
Pingli Liu, Wilmington, DE (US);
Jiacheng Zhou, Newark, DE (US);
Assignee:
Incyte Corporation, Wilmington, DE (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/535 (2006.01); C07D 413/04 (2006.01); C07D 498/04 (2006.01);
U.S. Cl.
CPC ...
C07D 498/04 (2013.01); C07D 413/04 (2013.01); A61K 31/535 (2013.01);
Abstract
The present invention relates to an amorphous solid form of (4S)-7-(3,5-dimethylisoxazol-4-yl)-4-pyridin-2-yl-4,5-dihydroimidazo[1,5,4-de][1,4]benzoxazin-2(1H)-one, and processes for its preparation, which is an inhibitor of BET proteins such as BRD2, BRD3, BRD4, and BRD-t and is useful in the treatment of various diseases such as cancer.