The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 25, 2019

Filed:

Mar. 07, 2016
Applicants:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Jongwon Lim, Lexington, MA (US);

Michael D. Altman, Needham, MA (US);

Jason D. Brubaker, Cambridge, MA (US);

Craig R. Gibeau, Holliston, MA (US);

Inventors:

Jongwon Lim, Lexington, MA (US);

Michael D. Altman, Needham, MA (US);

Jason D. Brubaker, Cambridge, MA (US);

Craig R. Gibeau, Holliston, MA (US);

Assignee:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/519 (2006.01); C07D 487/04 (2006.01); A61K 31/4162 (2006.01); C07D 519/00 (2006.01); A61K 31/55 (2006.01); A61K 31/551 (2006.01); A61K 31/553 (2006.01); A61K 45/06 (2006.01); A61P 29/00 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61K 31/4162 (2013.01); A61K 31/519 (2013.01); A61K 31/55 (2013.01); A61K 31/551 (2013.01); A61K 31/553 (2013.01); A61K 45/06 (2013.01); A61P 29/00 (2018.01); C07D 519/00 (2013.01);
Abstract

The present invention relates to pyrazolopyrimidine inhibitors of IRAK4 of formula (I) and provides compositions comprising such inhibitors, as well as methods therewith for treating IRAK4-mediated or -associated conditions or diseases.


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