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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10329283 B1

PDFFull Text
Date of Patent:
Jun. 25, 2019

Filed:

Jun. 27, 2016

G protein-coupled receptor kinase inhibitors and methods for use of the same

Applicant:

The Regents of the University of Michigan, Ann Arbor, MI (US);

Inventors:

Scott D. Larsen, South Lyon, MI (US);

John J. G. Tesmer, Ann Arbor, MI (US);

Helen Waldschmidt, Ann Arbor, MI (US);

Kristoff Homan, Newton, MA (US);

Michael William Wilson, Ann Arbor, MI (US);

Assignee:

THE REGENTS OF THE UNIVERSITY OF MICHIGAN, Ann Arbor, MI (US);

Attorney:

Marshall, Gerstein & Borun LLP

Primary Examiner:

Shawquia Jackson

Int. Cl.
CPC ...
C07D 405/14 (2006.01); C07D 401/14 (2006.01); C07D 401/12 (2006.01); C07D 405/12 (2006.01); A61P 9/00 (2006.01); A61P 9/12 (2006.01);
U.S. Cl.
CPC ...
C07D 405/14 (2013.01); A61P 9/00 (2018.01); A61P 9/12 (2018.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 405/12 (2013.01);
Abstract

Disclosed herein are novel GRK inhibitors and methods for their use in treating or preventing heart disease, such as cardiac failure, cardiac hypertrophy, and hypertension. In particular, disclosed herein are compounds of Formula (I) and pharmaceutically acceptable salt thereof, wherein the substituents are as described.

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Quick Actions:

Larsen, Scott. (2019). G protein-coupled receptor kinase inhibitors and methods for use of the same (U.S. Patent No. 10329283). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10329283

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