The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 25, 2019

Filed:

Jun. 14, 2018
Applicants:

Forma Tm, Llc, Watertown, MA (US);

Genentech, Inc., South San Francisco, CA (US);

Inventors:

Kenneth W. Bair, Wellesley, MA (US);

Timm R. Baumeister, Watertown, MA (US);

Alexandre J. Buckmelter, Acton, MA (US);

Karl H. Clodfelter, Watertown, MA (US);

Bingsong Han, North Haven, CT (US);

Jian Lin, Acton, MA (US);

Dominic J. Reynolds, Watertown, MA (US);

Chase C. Smith, Rutland, MA (US);

Zhongguo Wang, Lexington, MA (US);

Xiaozhang Zheng, Lexington, MA (US);

Po-Wai Yuen, Beijing, CN;

Assignees:

FORMA TM, LLC, Watertown, MA (US);

Genentech, Inc., South San Francisco, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/12 (2006.01); C07D 471/04 (2006.01); C07D 213/54 (2006.01); C07D 213/75 (2006.01); C07D 213/81 (2006.01); C07C 317/42 (2006.01); C07D 213/74 (2006.01); C07D 213/84 (2006.01); A61K 31/437 (2006.01); A61K 31/44 (2006.01); A61K 31/4406 (2006.01); A61K 31/4545 (2006.01); A61K 31/5377 (2006.01); A61K 45/06 (2006.01); C07D 213/40 (2006.01);
U.S. Cl.
CPC ...
C07D 401/12 (2013.01); A61K 31/437 (2013.01); A61K 31/44 (2013.01); A61K 31/4406 (2013.01); A61K 31/4545 (2013.01); A61K 31/5377 (2013.01); A61K 45/06 (2013.01); C07C 317/42 (2013.01); C07D 213/40 (2013.01); C07D 213/54 (2013.01); C07D 213/74 (2013.01); C07D 213/75 (2013.01); C07D 213/81 (2013.01); C07D 213/84 (2013.01); C07D 471/04 (2013.01);
Abstract

The present invention relates to compounds and compositions for the inhibition of NAMPT, their synthesis, applications and antidotes. An embodiment of the invention is the provision of a compound of Formula IIIA.


Find Patent Forward Citations

Loading…