The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 25, 2019
Filed:
Jan. 24, 2019
Applicant:
Bracco Imaging S.p.a., Milan, IT;
Inventors:
Silvio Aime, Carignano, IT;
Daniela Delli Castelli, Bibiana, IT;
Franco Fedeli, Vimodrone, IT;
Dario Livio Longo, Manta, IT;
Enzo Terreno, Bibiana, IT;
Fulvio Uggeri, Codogno, IT;
Assignee:
BRACCO IMAGING S.P.A., Milan, IT;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61B 5/055 (2006.01); A61K 49/10 (2006.01); G01R 33/56 (2006.01);
U.S. Cl.
CPC ...
A61K 49/106 (2013.01); A61K 49/101 (2013.01); A61K 49/108 (2013.01); G01R 33/5601 (2013.01);
Abstract
The present invention relates to the use of non-equivalent mobile protons belonging to NMR distinguishable steroisomers of a CEST agent in a ratiometric based CEST imaging procedure and to Lanthanide (III) complex compounds displaying at least two NMR-distinguishable steroisomers in solution useful as concentration independent CEST responsive agents.