The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 25, 2019
Filed:
Mar. 09, 2015
Applicant:
Dana-farber Cancer Institute, Inc., Boston, MA (US);
Inventors:
Bruce M. Spiegelman, Waban, MA (US);
James Lo, Charlestown, MA (US);
Assignee:
Dana-Farber Cancer Institute, Inc., Boston, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/48 (2006.01); A61K 48/00 (2006.01); C12Q 1/37 (2006.01); C12Q 1/6883 (2018.01); G01N 33/573 (2006.01);
U.S. Cl.
CPC ...
A61K 38/482 (2013.01); C12Q 1/37 (2013.01); C12Q 1/6883 (2013.01); C12Y 304/21046 (2013.01); G01N 33/573 (2013.01); A61K 48/00 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/118 (2013.01); C12Q 2600/156 (2013.01); C12Q 2600/158 (2013.01); G01N 2333/4716 (2013.01); G01N 2333/96433 (2013.01); G01N 2800/042 (2013.01);
Abstract
The present invention provides compositions and methods for regulating pancreatic beta cell function through modulation of adipsin activity and/or expression. Also provided are methods for preventing, treating, diagnosing, and prognosing metabolic disorders, such as diabetes, in a subject through modulation or detection of adipsin activity and/or expression.