The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 25, 2019
Filed:
Jul. 10, 2016
Hadasit Medical Research Services and Development Ltd., Jerusalem, IL;
Ben-gurion University of the Negev Research and Development Authority, Beer-Sheva, IL;
Yaron Ilan, Kfar-Tavor, IL;
Gadi Lalazar, Mevasseret Zion, IL;
Eyal Shteyer, Mevaseret Zion, IL;
Ami Ben-Ya'acov, Jerusalem, IL;
Smadar Cohen, Beer-Sheva, IL;
Tsiona Elkayam, Mobile Post Negev, IL;
Hadasit Medical Research Services and Development Ltd., Jerusalem, IL;
Ben-Gurion University of the Negev Research and Development Authority, Beer-Sheva, IL;
Abstract
The present invention relates to methods for the treatment of hepatic disorders in a subject in need thereof. More specifically, the methods of the invention are based on the administration, preferably, systemic administration, of a therapeutically effective amount of at least one biocompatible alginate biomaterial, any modification thereof and any combination thereof. The invention further provides methods for sustaining serum albumin levels, and/or reducing serum AST and ALT, in subjects suffering from hepatic disorder. Still further, the invention provides methods for reducing apoptosis and inducing cell proliferation in a damaged liver tissue of a subject suffering of hepatic disorder, using the alginate biomaterial described by the invention.