The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 25, 2019

Filed:

Dec. 23, 2015
Applicant:

Fgh Biotech, Inc., Houston, TX (US);

Inventors:

Motonari Uesugi, Osaka, JP;

Joel Huff, Spring Branch, TX (US);

Assignee:

FGH BIOTECH, INC., Houston, TX (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/44 (2006.01); C07D 401/14 (2006.01); C07D 401/04 (2006.01); C07D 413/04 (2006.01); C07D 417/04 (2006.01); C07D 417/06 (2006.01); C07D 417/14 (2006.01); A61K 31/41 (2006.01); A61K 31/422 (2006.01); A61K 31/427 (2006.01); A61K 31/454 (2006.01); A61K 31/4545 (2006.01); A61K 31/497 (2006.01); A61P 3/06 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/44 (2013.01); A61K 31/41 (2013.01); A61K 31/422 (2013.01); A61K 31/427 (2013.01); A61K 31/454 (2013.01); A61K 31/4545 (2013.01); A61K 31/497 (2013.01); A61P 3/06 (2018.01); A61P 35/00 (2018.01); C07D 401/04 (2013.01); C07D 401/14 (2013.01); C07D 413/04 (2013.01); C07D 417/04 (2013.01); C07D 417/06 (2013.01); C07D 417/14 (2013.01);
Abstract

The present invention relates to compounds, pharmaceutical compositions and formulations that have a structure (I). The compounds comprise a heterocyclic ring where W, X, Y, and Z generally and independently are S, N or C with the proviso that at least 2 of these positions in the ring are other than carbon. A pyridine or a substituted pyridine A ring and a phenyl or a substituted phenyl B ring are covalently bonded to the heterocyclic ring. Further provided are methods for treating a metabolic disorder, cell proliferative disease, reducing body weight or increasing thermogenesis during weight loss with the compounds of structure as described or pharmaceutically acceptable salt or stereoisomer thereof or both.


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