The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 25, 2019
Filed:
Apr. 03, 2015
Applicant:
Amgen, Inc., Thousand Oaks, CA (US);
Inventors:
Sean Caenepeel, Woodland Hills, CA (US);
Angela Coxon, Moorpark, CA (US);
Zhiqiang Du, Thousand Oaks, CA (US);
Paul Hughes, Santa Monica, CA (US);
Robert Loberg, Thousand Oaks, CA (US);
Gataree Ngarmchamnanrith, Thousand Oaks, CA (US);
Beate Sable, Newbury Park, CA (US);
Assignee:
Amgen, Inc., Thousand Oaks, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4375 (2006.01); C12Q 1/6886 (2018.01);
U.S. Cl.
CPC ...
A61K 31/4375 (2013.01); C12Q 1/6886 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/154 (2013.01); C12Q 2600/158 (2013.01);
Abstract
The present invention relates to methods of therapeutic treatment of cancer using selective tyrosine kinase inhibitors and cancer biomarkers, such as MET amplification and high Met expression for patient selection.