The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 25, 2019
Filed:
Apr. 11, 2018
Applicant:
Nanopharmaceuticals Llc, Rensselaer, NY (US);
Inventors:
Shaker Mousa, Wynantskill, NY (US);
Mehdi Rajabi, Albany, NY (US);
Ozlem O. Karakus, Glenmont, NY (US);
Assignee:
NANOPHARMACEUTICALS, LLC., Rensselaer, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/198 (2006.01); A61P 35/00 (2006.01); A61K 47/22 (2006.01); A61K 31/191 (2006.01); A61K 47/16 (2006.01); A61K 47/10 (2017.01);
U.S. Cl.
CPC ...
A61K 31/198 (2013.01); A61K 47/22 (2013.01); A61P 35/00 (2018.01); A61K 31/191 (2013.01); A61K 47/10 (2013.01); A61K 47/16 (2013.01);
Abstract
Chemical compositions and methods of synthesis thereof. The compositions disclosed and described herein are directed toward thyroid hormone αvβ3 integrin receptor antagonists conjugated to targets of the norepinephrine transporter (NET) or the catecholamine transporter. The compositions have a dual targeting effect and increased targeting efficiency in the treatment and diagnostic imaging of neuroendocrine tumors.