The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 25, 2019

Filed:

Jun. 02, 2014
Applicants:

Biosurfaces, Inc., Ashland, MA (US);

Clemson University, Clemson, SC (US);

Rhode Island Board of Education, Providence, RI (US);

Inventors:

Matthew D. Phaneuf, Ashland, MA (US);

Philip J. Brown, Williamston, SC (US);

Martin J. Bide, Hope Valley, RI (US);

Assignees:

BIOSURFACES, INC., Ashland, MA (US);

RHODE ISLAND BOARD OF EDUCATION, Providence, RI (US);

CLEMSON UNIVERSITY, Clemson, SC (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/70 (2006.01); A61K 31/4196 (2006.01); A61K 31/337 (2006.01); A61K 31/496 (2006.01); A61K 9/00 (2006.01); D04H 1/435 (2012.01); D04H 1/728 (2012.01); D04H 3/011 (2012.01); D04H 3/02 (2006.01); D04H 3/16 (2006.01); D01D 1/02 (2006.01); D01D 5/00 (2006.01); D01F 6/62 (2006.01); B29C 48/05 (2019.01); A61F 2/82 (2013.01); B29C 48/00 (2019.01);
U.S. Cl.
CPC ...
A61K 9/7007 (2013.01); A61K 9/0092 (2013.01); A61K 31/337 (2013.01); A61K 31/4196 (2013.01); A61K 31/496 (2013.01); B29C 48/05 (2019.02); D01D 1/02 (2013.01); D01D 5/0038 (2013.01); D01F 6/62 (2013.01); D04H 1/435 (2013.01); D04H 1/728 (2013.01); D04H 3/011 (2013.01); D04H 3/02 (2013.01); D04H 3/16 (2013.01); A61F 2/82 (2013.01); A61K 9/70 (2013.01); B29C 48/022 (2019.02);
Abstract

The present invention is a bioactive, nanofibrous material construct which is manufactured using a unique electrospinning perfusion methodology. One embodiment provides a nanofibrous biocomposite material formed as a discrete textile fabric from a prepared liquid admixture of (i) a non-biodegradable durable synthetic polymer; (ii) a biologically active agent; and (iii) a liquid organic carrier. These biologically-active agents are chemical compounds which retain their recognized biological activity both before and after becoming non-permanently bound to the formed textile material; and will become subsequently released in-situ as discrete freely mobile agents from the fabric upon uptake of water from the ambient environment.


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