The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 18, 2019
Filed:
Apr. 10, 2015
Applicant:
Yale University, New Haven, CT (US);
Inventors:
Irina Buhimschi, Columbus, OH (US);
Catalin S. Buhimschi, Columbus, OH (US);
Michael Choma, Hamden, CT (US);
Hemant Tagare, North Haven, CT (US);
Stephan Michael Jonas, Asldorf, DE;
Assignee:
Yale University, New Haven, CT (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/52 (2006.01); G01N 33/68 (2006.01); C09B 69/10 (2006.01); G01N 21/78 (2006.01);
U.S. Cl.
CPC ...
G01N 33/689 (2013.01); G01N 33/52 (2013.01); G01N 33/6839 (2013.01); C09B 69/106 (2013.01); G01N 21/78 (2013.01); G01N 2800/368 (2013.01);
Abstract
Various aspects and embodiments of the present disclosure are directed to methods and compositions (e.g., kits) for the identification of subjects with misfolded proteins in their urine. For example, methods and compositions for determining that a urine sample from a pregnant woman contains or does not contain misfolded are provided. In some embodiments, the presence of misfolded proteins in a urine sample from a pregnant woman is an indication of preeclampsia.