The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 18, 2019
Filed:
Oct. 20, 2017
Applicant:
Acorda Therapeutics, Inc., Ardsley, NY (US);
Inventors:
Anthony O. Caggiano, Larchmont, NY (US);
Jennifer Iaci, Boonton, NJ (US);
Andrea Vecchione, Mt. Vernon, NY (US);
Elizabeth Hunter, Manchester, GB;
Assignee:
Acorda Therapeutics, Inc., Ardsley, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/88 (2006.01); A61K 38/51 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C12N 9/88 (2013.01); A61K 38/51 (2013.01); C12Y 402/02004 (2013.01); A61K 38/00 (2013.01);
Abstract
One aspect of the present invention relates to mutants of chondroitinase ABCI. Such chondroitinase ABCI mutants exhibit altered chondroitin lyase activity or increased resistance to inactivation from stressors including exposure to UV light or heat. Methods of using chondroitinase ABCI mutant enzymes are also provided.