The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 18, 2019

Filed:

Oct. 22, 2015
Applicant:

Janssen Pharmaceutica NV, Beerse, BE;

Inventors:

George Hynd, Essex, GB;

Patrizia Tisselli, Essex, GB;

Calum Macleod, Essex, GB;

Samuel Edward Mann, Essex, GB;

John Gary Montana, Essex, GB;

Stephen Colin Price, Essex, GB;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61P 35/00 (2006.01); C07D 519/00 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 519/00 (2013.01); A61P 35/00 (2018.01);
Abstract

The present invention relates to pharmaceutical agents useful for therapy and/or prophylaxis in a mammal, and in particular to inhibitors of NF-κB-inducing kinase (NIK—also known as MAP3K14) useful for treating diseases such as cancer, inflammatory disorders, metabolic disorders and autoimmune disorders. The invention is also directed to pharmaceutical compositions comprising such compounds, to processes to prepare such compounds and compositions, and to the use of such compounds or pharmaceutical compositions for the prevention or treatment of diseases such as cancer, inflammatory disorders, metabolic disorders including obesity and diabetes, and autoimmune disorders.


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