The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 18, 2019
Filed:
Dec. 20, 2016
Applicant:
Janssen Pharmaceutica NV, Beerse, BE;
Inventors:
Ruben De Keyser, Beerse, BE;
Stijn Laps, Beerse, BE;
Thomas Joachim Landewald Rammeloo, Beerse, BE;
Koen Johan Herman Weerts, Beerse, BE;
Assignee:
Janssen Pharmaceutica NV, Beerse, BE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 409/00 (2006.01); C07D 409/10 (2006.01);
U.S. Cl.
CPC ...
C07D 409/10 (2013.01); C07B 2200/13 (2013.01);
Abstract
The present invention relates to an improved crystallization procedure to obtain canagliflozin hemihydrate crystals having a narrow particle size distribution by removing a small part of the crystalline suspension in the crystallization vessel from said vessel and subjecting said part to particle size reduction of the formed crystals followed by heating and reintroducting said part of the crystalline suspension again in the crystallization vessel which is kept within a specific temperature range.