The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 18, 2019

Filed:

Dec. 19, 2017
Applicant:

Bayer Pharma Aktiengesellschaft, Berlin, DE;

Inventors:

Eva Maria Becker-Pelster, Wuppertal, DE;

Philipp Buchgraber, Berlin, DE;

Anja Buchmüller, Essen, DE;

Karen Engel, Roßdorf, DE;

Volker Geiss, Ratingen, DE;

Andreas Göller, Wuppertal, DE;

Herbert Himmel, Essen, DE;

Raimund Kast, Wuppertal, DE;

Andreas Knorr, Erkrath, DE;

Dieter Lang, Velbert, DE;

Gorden Redlich, Bochum, DE;

Carsten Schmeck, Mülheim, DE;

Hanna Tinel, Wuppertal, DE;

Frank Wunder, Wuppertal, DE;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 413/14 (2006.01); C07D 401/14 (2006.01); C07D 417/14 (2006.01); C07D 491/107 (2006.01); A61K 31/506 (2006.01); A61K 31/5377 (2006.01); A61K 31/541 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 401/14 (2013.01); A61K 31/506 (2013.01); A61K 31/5377 (2013.01); A61K 31/541 (2013.01); A61K 45/06 (2013.01); C07D 413/14 (2013.01); C07D 417/14 (2013.01); C07D 491/107 (2013.01);
Abstract

The present application relates to novel substituted piperidinyltetrahydroquinolines, to processes for their preparation, to their use for the treatment and/or prevention of diseases and to their use for preparing medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of diabetic microangiopathies, diabetic ulcers on the extremities, in particular for promoting wound healing of diabetic foot ulcers, diabetic heart failure, diabetic coronary microvascular heart disorders, peripheral and cardial vascular disorders, thromboembolic disorders and ischaemias, peripheral circulatory disturbances, Raynaud's phenomenon, CREST syndrome, microcirculatory disturbances, intermittent claudication, and peripheral and autonomous neuropathies.


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