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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10323018 B1

PDFFull Text
Expired
Date of Patent:
Jun. 18, 2019

Filed:

Jan. 20, 2016

Quinazoline and quinoline compounds and uses thereof

Applicant:

Millennium Pharmaceuticals, Inc., Cambridge, MA (US);

Inventors:

Brian Scott Freeze, Boston, MA (US);

Kenneth M. Gigstad, Westford, MA (US);

David A. Janowick, Quincy, MA (US);

Hong Myung Lee, Cambridge, MA (US);

Zhan Shi, Concord, MA (US);

Francois Soucy, Stoneham, MA (US);

Stepan Vyskocil, Arlington, MA (US);

Assignee:

Millennium Pharmaceuticals, Inc., Cambridge, MA (US);

Attorney:

McNeill Baur PLLC

Primary Examiner:

D Margaret M Seaman

Int. Cl.
CPC ...
C07D 401/14 (2006.01); A61K 31/47 (2006.01); C07D 403/12 (2006.01); C07D 405/14 (2006.01); C07D 401/12 (2006.01); C07D 403/14 (2006.01); C07D 409/14 (2006.01); C07D 471/04 (2006.01); C07D 495/04 (2006.01); A61K 31/4709 (2006.01); A61K 31/501 (2006.01); A61K 31/517 (2006.01); A61K 31/541 (2006.01); C07D 215/233 (2006.01); C07D 401/04 (2006.01); C07D 417/12 (2006.01);
U.S. Cl.
CPC ...
C07D 401/14 (2013.01); A61K 31/47 (2013.01); A61K 31/4709 (2013.01); A61K 31/501 (2013.01); A61K 31/517 (2013.01); A61K 31/541 (2013.01); C07D 215/233 (2013.01); C07D 401/04 (2013.01); C07D 401/12 (2013.01); C07D 403/12 (2013.01); C07D 403/14 (2013.01); C07D 405/14 (2013.01); C07D 409/14 (2013.01); C07D 417/12 (2013.01); C07D 471/04 (2013.01); C07D 495/04 (2013.01);
Abstract

This invention provides compounds of formula (I) or a pharmaceutically acceptable salt thereof, wherein T, J, R, R, R, o, R, W and Rand subsets thereof are as described in the specification. The compounds are inhibitors of NAMPT and are thus useful for treating cancer, inflammatory conditions, and/or T-cell mediated autoimmune disease.

Find Patent Forward Citations

Freeze, Brian. (2019). Quinazoline and quinoline compounds and uses thereof (U.S. Patent No. 10323018). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10323018

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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