The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 18, 2019
Filed:
Aug. 21, 2012
Roger Schibli, Baden, CH;
Rudolf Moser, Schaffhausen, CH;
Cristina Magdalena Muller, Nussbaumen, CH;
Simon Mensah Ametamey, Zurich, CH;
Cindy Ramona Fischer, Freising, DE;
Viola Groehn, Dachsen, CH;
Roger Schibli, Baden, CH;
Rudolf Moser, Schaffhausen, CH;
Cristina Magdalena Muller, Nussbaumen, CH;
Simon Mensah Ametamey, Zurich, CH;
Cindy Ramona Fischer, Freising, DE;
Viola Groehn, Dachsen, CH;
Merck & CIE, Schaffhausen, CH;
Abstract
The present invention is directed towards newF-folate radiopharmaceuticals, wherein theF isotope F is linked via a prosthetic group, more specifically via a prosthetic group having a saccharide group, such as a cyclic mono- or oligosaccharide, preferably based on a pyranoside or furanoside, which is covalently linked to the glutamate portion of a folate or derivative thereof, a method of their preparation, as well as their use in diagnosis and monitoring of cancer and inflammatory and autoimmune diseases and therapy thereof.