The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 18, 2019
Filed:
Feb. 09, 2018
Eisai R&d Management Co., Ltd., Tokyo, JP;
Earl F. Albone, Blue Bell, PA (US);
Xin Cheng, Wallingford, PA (US);
Daniel W. Custar, North Andover, MA (US);
Keiji Furuuchi, Wynnewood, PA (US);
Jing Li, Andover, MA (US);
Utpal Majumder, Andover, MA (US);
Toshimitsu Uenaka, West Chester, PA (US);
Eisai R&D Management Co., Ltd., Tokyo, JP;
Abstract
Linker toxins and antibody-drug conjugates that bind to human oncology antigen targets such as folate receptor alpha and/or provide anti-tubulin drug activity are disclosed. The linker toxins and antibody-drug conjugates comprise an eribulin drug moiety and can be internalized into target antigen-expressing cells. The disclosure further relates to methods and compositions for use in the treatment of cancer by administering the antibody-drug conjugates provided herein.