The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 18, 2019

Filed:

Nov. 12, 2015
Applicant:

University of Mississippi Medical Center, Jackson, MS (US);

Inventors:

Alejandro R. Chade, III, Brandon, MS (US);

Gene L. Bidwell, III, Jackson, MS (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/18 (2006.01); A61K 38/39 (2006.01); A61K 47/64 (2017.01); A61P 13/12 (2006.01);
U.S. Cl.
CPC ...
A61K 47/64 (2017.08); A61K 38/1866 (2013.01); A61K 38/39 (2013.01); A61K 47/6435 (2017.08); A61P 13/12 (2018.01);
Abstract

A composition including an elastin-like polypeptide (ELP) coupled to a kidney targeting peptide and. a therapeutic agent is provided. A method of delivering a therapeutic agent to a subject in need thereof comprising: administering to the subject an effective amount of a composition comprising: an elastin-like polypeptide (ELP), a kidney targeting agent coupled to the ELP and a targeting agent and/or a drug binding domain coupled to the ELP, wherein the ELP includes an amino acid sequence having at least about repeats of the amino acid sequence GVPGX (SEQ ID NO: 1), and wherein the composition enhances the deposition and retention of the therapeutic agent in the kidney relative to the non-conjugated therapeutic.


Find Patent Forward Citations

Chade, III, Alejandro. (2019). Kidney-targeted drug delivery systems (U.S. Patent No. 10322189). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10322189

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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