The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 18, 2019

Filed:

Jul. 15, 2015
Applicant:

National Central University, Taoyuan, TW;

Inventors:

Ruoh-Chyu Ruaan, Taipei, TW;

Ching-Wei Tsai, Taoyuan, TW;

Chuan-Hui Lu, Pingtung County, TW;

Yung Chang, Taoyuan, TW;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 7/06 (2006.01); A61K 47/48 (2006.01); A61K 31/704 (2006.01); A61K 47/60 (2017.01); A61K 47/64 (2017.01);
U.S. Cl.
CPC ...
A61K 47/48246 (2013.01); A61K 31/704 (2013.01); A61K 47/60 (2017.08); A61K 47/64 (2017.08); C07K 7/06 (2013.01); C07K 2319/10 (2013.01); C07K 2319/70 (2013.01);
Abstract

This invention is about a cell-penetrating drug carrier and the application thereof. The mentioned cell-penetrating drug carrier can approach the target cell through using a proper recognizable sequence, so that the cell-penetrating drug carrier can be used to specifically delivery wanted drug to target cell. Through carrying wanted drug into the cytoplasm of the target cell by cell-penetrating peptide, the drug accumulation volume in the target cell can be efficiently increased. Preferably, through using proper bioinert polymer, the cell-penetrating peptide and the recognizable sequence can be kept from been digested before approaching the target cell.


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