The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 18, 2019

Filed:

Aug. 11, 2014
Applicants:

The Trustees of Columbia University IN the City of New York, New York, NY (US);

The University of North Carolina AT Chapel Hill, Chapel Hill, NC (US);

Inventors:

Chen Chen, New York, NY (US);

Elisa E. Konofagou, New York, NY (US);

Paul Dayton, Chapel Hill, NC (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61M 37/00 (2006.01); A61K 41/00 (2006.01); A61B 17/20 (2006.01); A61K 9/00 (2006.01); A61K 9/50 (2006.01); A61K 9/51 (2006.01); A61N 7/00 (2006.01); A61B 17/22 (2006.01);
U.S. Cl.
CPC ...
A61K 41/0047 (2013.01); A61K 9/0009 (2013.01); A61K 9/0019 (2013.01); A61K 9/0043 (2013.01); A61K 9/5031 (2013.01); A61K 9/5146 (2013.01); A61M 37/0092 (2013.01); A61N 7/00 (2013.01); A61B 2017/22008 (2013.01); A61N 2007/0039 (2013.01);
Abstract

Techniques for opening a target tissue using nanodroplets are provided. An exemplary method can include targeting a region of tissue for opening, delivering a plurality of nanodroplets to the region, and applying an ultrasound beam at the region such that the nanodroplets cavitate, or convert to microbubbles that cavitate, thereby causing the target tissue to open.


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