The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 18, 2019

Filed:

Jun. 06, 2016
Applicant:

Evonik Roehm Gmbh, Darmstadt, DE;

Inventors:

Juan Tome-Alcalde, Madrid, ES;

Norbert Windhab, Hofheim, DE;

Melanie Liefke, Ober-Ramstadt, DE;

Anne Benedikt, Frankfurt, DE;

Jessica Müller-Albers, Darmstadt, DE;

Tom Tice, Indian Springs, AL (US);

Susanne Ullrich, Darmstadt, DE;

Andrea Engel, Frankfurt, DE;

Matthias Germer, Langen, DE;

Steffen Kistner, Frankfurt, DE;

Jens Daufenbach, Mainz, DE;

Assignee:

Evonik Roehm GmbH, Darmstadt, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61K 38/36 (2006.01); A61K 9/16 (2006.01); A61K 9/19 (2006.01); A61K 38/48 (2006.01); A61K 38/49 (2006.01); A61K 47/34 (2017.01); A61K 9/51 (2006.01);
U.S. Cl.
CPC ...
A61K 38/36 (2013.01); A61K 9/1647 (2013.01); A61K 9/19 (2013.01); A61K 38/4846 (2013.01); A61K 38/4866 (2013.01); A61K 38/49 (2013.01); A61K 9/5153 (2013.01); A61K 47/34 (2013.01);
Abstract

A process for preparing a powder, which includes one or more human coagulation factor proteins and a lactic acid polymer, involves mixing and dispersing a lactic acid polymer with a particle size din the range 0.1-2 μm and the one or more human coagulation factor proteins in water. The dispersion is dried, and the resulting dried mass is compressed. The resulting compressed dried mass is comminuted to a powder with a particle size din the range of more than 0.5 and up to 5 μm.


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