The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 18, 2019

Filed:

Jul. 13, 2017
Applicants:

Kite Pharma, Inc., Santa Monica, CA (US);

The United States of America, As Represented BY the Secretary, Department of Health and Human Services, Washington, DC (US);

Inventors:

Adrian Bot, Santa Monica, CA (US);

Jeffrey S. Wiezorek, Santa Monica, CA (US);

William Go, Santa Monica, CA (US);

Rajul Jain, Santa Monica, CA (US);

James N. Kochenderfer, Bethesda, MD (US);

Steven A. Rosenberg, Bethesda, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/17 (2015.01); A61K 38/20 (2006.01); A61K 45/06 (2006.01); A61P 35/02 (2006.01); A61K 31/664 (2006.01); A61K 31/675 (2006.01); A61K 31/7076 (2006.01);
U.S. Cl.
CPC ...
A61K 35/17 (2013.01); A61K 31/664 (2013.01); A61K 31/675 (2013.01); A61K 31/7076 (2013.01); A61K 38/2013 (2013.01); A61K 38/2053 (2013.01); A61K 45/06 (2013.01); A61P 35/02 (2018.01);
Abstract

The invention provides methods of increasing the efficacy of a T cell therapy in a patient in need thereof. The invention includes a method of conditioning a patient prior to a T cell therapy, wherein the conditioning involves administering a combination of cyclophosphamide and fludarabine.


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