The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 18, 2019

Filed:

Sep. 21, 2016
Applicants:

Commissariat a L'energie Atomique ET Aux Energies Alternatives, Paris, FR;

Institut National DE LA Sante ET DE LA Recherche Medicale (Inserm), Paris, FR;

Inventors:

Sofia Giacosa, La Tour du Pin, FR;

Catherine Pillet, Vif, FR;

Claude Cochet, Claix, FR;

Odile Filhol, Claix, FR;

Caroline Barette, Sassenage, FR;

Emmanuelle Soleilhac, Saint Etienne de Crossy, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 45/06 (2006.01); A61P 35/00 (2006.01); A61K 31/437 (2006.01); A61K 31/4375 (2006.01); A61K 31/4745 (2006.01); A61K 31/5377 (2006.01);
U.S. Cl.
CPC ...
A61K 31/5377 (2013.01); A61K 31/437 (2013.01); A61K 31/4375 (2013.01); A61K 31/4745 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01);
Abstract

The present invention pertains to a novel treatment of renal cell carcinoma and other a solid tumors which harbor a VHL inactivation, based on the combination of a first agent inhibiting a protein kinase CK2 (CK2) and a second agent inhibiting an Ataxia Telangiectasia Mutated (ATM) kinase.


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