The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 18, 2019
Filed:
Apr. 17, 2017
Jeffrey Alan Klein, San Juan Capistrano, CA (US);
Jeffrey Alan Klein, San Juan Capistrano, CA (US);
HK Pharma, San Clemente, CA (US);
Abstract
A method of subcutaneous delivery of a drug or a therapeutic agent to a subject comprising administering to said subject a mass of fluid of a tumescent composition comprising: (a) the drug or the therapeutic agent; (b) a vasoconstrictor; and (c) a pharmaceutically acceptable carrier, wherein a relatively large total amount of the drug is isolated from systemic circulation in the subject because only drug in an outer boundary of the mass of fluid is the available for absorption, whereas a portion of the drug located within a central portion of the mass of fluid is virtually isolated from the systemic circulation by virtue of profound capillary vasoconstriction, wherein epinephrine-induced vasoconstriction dramatically slows systemic absorption of the drug or therapeutic agent, and wherein the mass of fluid is a reservoir that delivers the drug or the therapeutic agent to the subject with pharmacokinetics that are analogous to a slow-release oral tablet or a slow constant intravenous (IV) Infusion.