The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 11, 2019
Filed:
Jun. 29, 2016
Seven Bridges Genomics, Inc., Cambridge, MA (US);
Peter Komar, Boston, MA (US);
Yilong Li, Cambridge, MA (US);
Seven Bridges Genomics, Inc., Charlestown, MA (US);
Abstract
A method and corresponding apparatus for identifying tandem repeats in a nucleotide sequence is described. Tandem repeats can be identified by identifying one or more lines present in a self-alignment plot of the nucleotide sequence. The disclosed method includes identifying one or more square-shaped subregions (SSS) representing a tandem repeat and each associated with a plurality of identified candidate alignments by: i) estimating a defining point of an individual square for each of the candidate alignments, each candidate alignment having a start point and an end point, the start point and the end point positioned along adjacent sides of the individual square; ii) selecting one or more seed alignments from the one or more candidate alignments; and iii) associating the one or more candidate alignments with the one or more seed alignments. Based on the associating, a final SSS representing a tandem repeat is determined and its presence is reported.