The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 11, 2019

Filed:

Jun. 30, 2016
Applicant:

The Regents of the University of California, Oakland, CA (US);

Inventors:

Laura Waller, Berkeley, CA (US);

Hillel Adesnik, Kensington, CA (US);

Nicolas Pegard, Berkeley, CA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
H04N 7/18 (2006.01); G02B 21/36 (2006.01); G06T 7/00 (2017.01); A61B 5/00 (2006.01); G02B 27/00 (2006.01); G02B 21/16 (2006.01); G02B 3/00 (2006.01);
U.S. Cl.
CPC ...
G02B 21/367 (2013.01); A61B 5/0042 (2013.01); A61B 5/0071 (2013.01); A61B 5/4064 (2013.01); A61B 5/743 (2013.01); G02B 27/0075 (2013.01); G06T 7/0016 (2013.01); A61B 5/7246 (2013.01); A61B 2560/0223 (2013.01); G02B 3/0056 (2013.01); G02B 21/16 (2013.01); G02B 21/361 (2013.01); G06T 2207/10016 (2013.01); G06T 2207/10052 (2013.01); G06T 2207/10056 (2013.01); G06T 2207/30016 (2013.01);
Abstract

A system and method for quantitative functional neuroimaging through thick brain tissue in live animals. A computational imaging method is disclosed that uses plenoptic image acquisition including a first initialization step that identifies individual neurons by their optical signature and provides a reliable estimate of their position in space and a second stimulation-based image processing step that used acquired calibration data to quickly quantify activity in each identified neuron at video frame-rate.


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