The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 11, 2019

Filed:

Mar. 10, 2016
Applicant:

Duke University, Durham, NC (US);

Inventors:

Svati H. Shah, Durham, NC (US);

Christopher B. Newgard, Durham, NC (US);

William E. Kraus, Durham, NC (US);

Elizabeth R. Hauser, Durham, NC (US);

Geoffrey S. Ginsburg, Durham, NC (US);

L. Kristin Newby, Durham, NC (US);

Assignee:

Duke University, Durham, NC (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G16H 50/30 (2018.01); G01N 33/68 (2006.01); A61B 5/00 (2006.01); A61B 5/145 (2006.01); G01N 21/78 (2006.01); H01J 49/00 (2006.01); G06F 19/00 (2018.01); G01N 21/77 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6887 (2013.01); A61B 5/00 (2013.01); A61B 5/14532 (2013.01); A61B 5/14546 (2013.01); A61B 5/4866 (2013.01); A61B 5/7275 (2013.01); G01N 21/78 (2013.01); G06F 19/00 (2013.01); G16H 50/30 (2018.01); H01J 49/0027 (2013.01); G01N 2021/7786 (2013.01); G01N 2800/324 (2013.01); G01N 2800/50 (2013.01); Y10T 436/174614 (2015.01); Y10T 436/200833 (2015.01); Y10T 436/201666 (2015.01);
Abstract

Methods of assessing the risk of cardiovascular disease in a subject by detecting the level of at least one metabolite in a sample from the subject are disclosed herein. The level of the metabolite is indicative of the risk of cardiovascular disease in the subject. The metabolites may be acylcarnitines, amino acids, ketones, free fatty acids or hydroxybutyrate. The cardiovascular disease may be risk of a cardiovascular event, presence of coronary artery disease or risk of development of coronary artery disease.


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