The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 11, 2019
Filed:
Aug. 31, 2016
Applicant:
Swift Biosciences, Inc., Ann Arbor, MI (US);
Inventors:
Vladimir Makarov, Ann Arbor, MI (US);
Julie Laliberte, Ypsilanti, MI (US);
Assignee:
Swift Biosciences, Inc., Ann Arbor, MI (US);
Primary Examiner:
Int. Cl.
CPC ...
C12P 19/34 (2006.01); C12Q 1/686 (2018.01); C12N 15/66 (2006.01); C12Q 1/6886 (2018.01); C12Q 1/6855 (2018.01); C12Q 1/6874 (2018.01); C12Q 1/6869 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/686 (2013.01); C12N 15/66 (2013.01); C12Q 1/6855 (2013.01); C12Q 1/6869 (2013.01); C12Q 1/6874 (2013.01); C12Q 1/6886 (2013.01); C12Q 2521/501 (2013.01); C12Q 2521/525 (2013.01); C12Q 2521/531 (2013.01); C12Q 2525/186 (2013.01); C12Q 2525/191 (2013.01);
Abstract
Methods for the preparation of PCR reaction mixtures and for performing multiplex PCR amplification which limit the production of non-target amplicons are provided. Production of non-target amplicons is limited because the non-target amplicons have complementary 5' and 3′ ends as a result of the target-specific primer designs such that the non-target amplicons can form stable secondary structure during the annealing step.