The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 11, 2019

Filed:

Jan. 29, 2016
Applicant:

Abbvie Inc., North Chicago, IL (US);

Inventors:

Michael J. Abrahamson, Chicago, IL (US);

Angelica B. Kielbus, Evanston, IL (US);

William T. Riordan, Libertyville, IL (US);

David R. Hill, Gurnee, IL (US);

Sanjay R. Chemburkar, Gurnee, IL (US);

Rajarathnam E. Reddy, Gurnee, IL (US);

Timothy B. Towne, Lindenhurst, IL (US);

Jianzhang Mei, Lake Forest, IL (US);

Gareth J. Brown, Antrim, GB;

Stefan Mix, Belfast, GB;

Assignee:

Abb Vie Inc., North Chicago, IL (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12P 7/62 (2006.01);
U.S. Cl.
CPC ...
C12P 7/62 (2013.01);
Abstract

Disclosed are methods of synthesizing enantioenriched difluoroalkylcyclopropyl amino esters and their salts, such as the dicyclohexylamine salt of (1S,2R)-2-(difluoromethyl)-1-(propoxycarbonyl)cyclopropane carboxylic acid. These compounds are useful intermediates in the synthesis of viral protease inhibitors.


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