The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 11, 2019

Filed:

Mar. 17, 2016
Applicants:

Agency for Science, Technology and Research, Singapore, SG;

National University of Singapore, Singapore, SG;

Inventors:

Cheng-I Wang, Singapore, SG;

Katja Fink, Singapore, SG;

Paul Macary, Singapore, SG;

Roland Zuest, Singapore, SG;

Meihui Xu, Singapore, SG;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/10 (2006.01); G01N 33/569 (2006.01); A61P 31/12 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/1081 (2013.01); A61P 31/12 (2018.01); G01N 33/56983 (2013.01); A61K 2039/505 (2013.01); C07K 2317/34 (2013.01); C07K 2317/76 (2013.01); G01N 2333/185 (2013.01); Y02A 50/386 (2018.01); Y02A 50/53 (2018.01);
Abstract

Disclosed are isolated antibodies, or antigen binding fragments thereof, that bind to dengue virus epitopes, as well as kits containing them, compositions containing them, and passive vaccines comprising them, in one embodiment, the antibody or antigen binding fragment thereof is capable of binding to a whole dengue virus particle better than binding to a dengue virus surface glycoprotein. Also disclosed are methods of using the antibodies or antigen binding fragments thereof, nucleic acids encoding them, vectors expressing the nucleic acids, host producing them, and methods of manufacturing them.


Find Patent Forward Citations

Loading…