The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 11, 2019
Filed:
Feb. 17, 2018
Applicant:
Sapience Therapeutics, Inc., Harrison, NY (US);
Inventors:
Barry Jay Kappel, Pelham, NY (US);
Jimmy Andrew Rotolo, Port Washington, NY (US);
Gene Merutka, Phoenixville, PA (US);
Assignee:
Sapience Therapeutics, Inc., Harrison, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/58 (2006.01); C07K 14/82 (2006.01); C07K 14/47 (2006.01); A61P 35/00 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/82 (2013.01); A61P 35/00 (2018.01); C07K 14/4705 (2013.01); A61K 38/00 (2013.01); C07K 2319/10 (2013.01);
Abstract
Provided are cell-penetrating ATF5 polypeptides having a cell-penetrating region and an ATF5 leucine zipper region, compositions comprising the ATF5 polypeptides, and methods of treating a tumor and promoting cytotoxicity in a neoplastic cell using the ATF5 polypeptides.