The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 11, 2019

Filed:

Oct. 03, 2014
Applicants:

Oregon Health & Science University, Portland, OR (US);

The United States of America As Represented BY the Department of Veterans Affairs, Washington, DC (US);

Inventors:

Arthur A. Vandenbark, Portland, OR (US);

Roberto Meza-Romero, Hillsboro, OR (US);

Gil Benedek, Portland, OR (US);

Gregory G. Burrows, Portland, OR (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); C07K 14/705 (2006.01); C07K 14/74 (2006.01); A61K 39/008 (2006.01); C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
C07K 14/705 (2013.01); A61K 39/0008 (2013.01); C07K 14/70539 (2013.01); A61K 2039/605 (2013.01); A61K 2039/627 (2013.01); C07K 2319/35 (2013.01);
Abstract

Recombinant polypeptides comprising a DRα1 domain, an antigenic peptide, and a linker sequence are disclosed. The linker sequence comprises a first glycine-serine spacer, a thrombin cleavage site and a second glycine-serine spacer. Further disclosed are pharmaceutical compositions comprising the recombinant polypeptides, methods of treating inflammatory disease using said pharmaceutical compositions, and expression constructs comprising nucleic acids that encode the recombinant polypeptides.


Find Patent Forward Citations

Vandenbark, Arthur. (2019). Recombinant polypeptides comprising mhc class ii α1 domains (U.S. Patent No. 10316075). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10316075

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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