The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 11, 2019

Filed:

Jun. 02, 2015
Applicant:

Glaxosmithkline Intellectual Property (No. 2) Limited, Brentford, Middlesex, GB;

Inventors:

Bruce G. Szczepankiewicz, Hopkinton, MA (US);

Karsten Koppetsch, Woburn, MA (US);

Robert B. Perni, Marlborough, MA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A01N 43/04 (2006.01); A61K 31/70 (2006.01); C07H 19/048 (2006.01); C07H 1/00 (2006.01); C07H 1/06 (2006.01);
U.S. Cl.
CPC ...
C07H 19/048 (2013.01); C07H 1/00 (2013.01); C07H 1/06 (2013.01); C07B 2200/13 (2013.01);
Abstract

Provided herein are crystalline beta-D-nicotinamide riboside chloride compositions and methods of preparation and use thereof. Also provided are related pharmaceutical compositions and methods of use thereof. The crystalline beta-D-nicotinamide riboside chloride compositions may be used to treat a disease or disorder that would benefit from increased NAD levels including a mitochondrial disease or disorder, insulin resistance, a metabolic syndrome, diabetes, obesity, or for increasing insulin sensitivity in a subject.


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