The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 11, 2019
Filed:
Jul. 07, 2015
Zhejiang Hisun Pharmaceutical Co., Ltd., Taizhou, Zhejiang, CN;
Huijun Ren, Shanghai, CN;
Daochao Li, Shanghai, CN;
Xuexiao Ying, Shanghai, CN;
Feng Chen, Shanghai, CN;
Linghui Zheng, Shanghai, CN;
Lingping Wang, Shanghai, CN;
Hua Bai, Shanghai, CN;
ZHEJIANG HISUN PHARMACEUTICAL CO., LTD., Taizhou, Zhejiang, CN;
Abstract
A fidaxomicin purification method, comprising: fermentingsp. HS-16-20 to generate fermented liquid; conducting solid/liquid separation on the fermented liquid, soaking mycelium in an organic solvent, and filtering to obtain a solution containing fidaxomicin; treating the solution with nanofiltration concentrate, and separating to obtain fidaxomicin crude product; conducting preparative column chromatography on the fidaxomicin crude product, eluting with an acid aqueous solution containing an organic solvent, and separating to obtain the refined fidaxomicin product.